Publications & documentation

Research

Publications, technical documentation, research notes, and institutional releases from NaS.

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7 entries
Microscopy-informed conceptual illustration of irregular breast-cancer cells with heterogeneous nuclei and extracellular matrix
Computational Oncology

Research Report

Technical-repeat sensitivity of fixed-reference PAM50 subtyping

A public-data computational study of whether one frozen PAM50 method returns the same breast-cancer subtype label for repeated measurements linked to the same reported tumor RNA source.

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Conceptual printed DNA letters on textured white paper, with one gold A; illustrative sequence, not an observed RNU4-2 variant
Computational Genomics

Research Note

AlphaGenome Atlas in RNU4-2: a focused computational benchmark

We compared AlphaGenome Atlas variant-impact scores with published experimental effects in RNU4-2. A focused benchmark of 435 transcript variants, with reproducible analysis and clearly stated limits.

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Smoked glass layers with a satin gold center on charcoal
Healthcare Operations

White Paper

Introducing NaS Denials

A specialty denial prevention and appeals platform designed to connect payer policy, clinical evidence, human review, and payment outcomes in one accountable workflow.

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Community

Institutional Essay

Why Hyde Park

Why NaS is being built in Hyde Park: a place our founder calls home, a community shaped by inquiry and creativity, and a responsibility to serve Chicago’s South Side.

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The NaS gold emblem
Institutional

Institutional Essay

Why NaS Exists

Why NaS was created, the technological mismatch that shaped our beginning, and our ambition to place extraordinary tools in the hands of people pursuing extraordinary questions.

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Illustration of the cerebral cortex with natural folds and fine surface vessels
Scientific Infrastructure

White Paper

The NaS Cortex: A Knowledge Architecture for the Life Sciences

A knowledge architecture for the life sciences built around eight domain-specific gyri, sparse expert activation, incremental training, and a staged compute roadmap for Nicole.

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Institutional

Release

Chicago: Our Chosen Home

Why NaS Research chose Chicago: a life-science, medical, manufacturing, educational, and global city with the depth required to build a durable scientific institution.

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