Research
Research areas
Publications
The ClinVar Conflict Atlas
Measuring the severity, distribution, and observed persistence of germline classification disagreement across three preserved ClinVar snapshots.
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Publications
Testing the limits of blood-brain barrier prediction
How chemical similarity and model confidence shape reliability beyond the benchmark.
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Publications
Technical-repeat sensitivity of fixed-reference PAM50 subtyping
A public-data computational study of whether one frozen PAM50 method returns the same breast-cancer subtype label for repeated measurements linked to the same reported tumor RNA source.
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The NaS Cortex: A Knowledge Architecture for the Life Sciences
A knowledge architecture for the life sciences built around eight domain-specific gyri, sparse expert activation, incremental training, and a staged compute roadmap for Nicole.
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