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Atorvastatin

LipitorHMG-CoA reductase inhibitorOral tablet

Mechanism

Inhibits HMG-CoA reductase, reducing hepatic cholesterol synthesis and increasing LDL receptor activity.

Uses

  • Lowering LDL cholesterol
  • Reducing cardiovascular risk
  • Mixed dyslipidemia

Common effects

  • Muscle aches
  • Diarrhea
  • Joint discomfort
  • Nasopharyngitis

Serious risks

  • Myopathy and rhabdomyolysis
  • Hepatic injury
  • Clinically important drug interactions

Monitoring

  • Lipid response
  • Unexplained muscle symptoms
  • Liver testing when clinically indicated
  • Interaction changes

Counseling

  • Take consistently each day
  • Report unexplained muscle pain or weakness
  • Discuss pregnancy and breastfeeding plans
  • Check before starting interacting medicines
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