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Module 12310 lessonsRxPrep 2023 Chapter 39, current CDC rabies, tetanus, Capnocytophaga, and blood-exposure guidance, IDSA bite-wound guidance, and NICE antimicrobial stewardship guidance

Animal and Human Bites

Assess dog, cat, and human bites, protect deep anatomy, reduce bacterial inoculation, select preemptive or treatment antibiotics, prevent tetanus and rabies, evaluate blood exposure, and close the follow-up loop.

01

Triage bite wounds by life threat, anatomy, mechanism, species, exposure route, and host risk.

02

Differentiate dog crush injury, cat puncture inoculation, direct human bites, and closed-fist injuries.

03

Use immediate cleansing, irrigation, exploration, debridement, and closure principles without replacing source control with medication.

04

Select antibiotic prophylaxis and treatment by wound risk, oral flora, allergy, organ function, severity, and follow-up.

05

Apply current public-health rabies assessment, HRIG, vaccine, tetanus, and bloodborne-exposure pathways.

06

Recognize infection, deep-space disease, systemic toxicity, safeguarding concerns, and failure requiring escalation.

123.01

Triage the Person Before the Bite

Bite care begins with hemorrhage, shock, airway, anatomy, function, time, animal context, exposure biology, and host reserve rather than a product recommendation.

What to learn
  • Hemorrhage
  • Deep anatomy
  • Species
  • Exposure route
  • Host risk
Exposure triageIdentify life threats, anatomy, exposure biology, and time-sensitive prevention
01StabilizeBleeding and major trauma

Life threats come first

02MapSpecies, mechanism, site

Surface size can mislead

03TestMotion, sensation, perfusion

Protect deep structures

04PreventTetanus, rabies, blood exposure

Start clocks early

Stabilize life threats

Activate emergency services for uncontrolled bleeding, shock, airway or neck injury, amputation, major tissue loss, or penetrating chest, abdominal, pelvic, or neurovascular trauma.

Map the wound

Record species, mechanism, time, site, depth, contamination, tissue loss, bleeding, pain, and whether teeth or foreign material may remain.

Test anatomy and function

Check active motion, strength, sensation, perfusion, joint pain, tendon excursion, and distal neurovascular status. Small openings can conceal major damage.

Start prevention clocks

Document tetanus series, rabies-relevant exposure, animal availability, visible blood, hepatitis B immunity, immune status, and time since exposure.

0 of 1 answered
01Which finding requires emergency care before routine bite cleansing?
Answer every question to submit.
123.02

Read the Injury Pattern Left by Teeth

Dog bites more often crush and tear, while cat bites commonly create deep narrow punctures. Anatomy and host biology determine how much danger hides below the surface.

What to learn
  • Crush
  • Puncture
  • Devitalized tissue
  • Hand anatomy
  • Capnocytophaga
Mechanism mapCrush, tear, puncture, inoculation, and host risk create different wounds
01DogCrush and laceration

Inspect devitalized tissue

02CatDeep narrow puncture

Assume hidden inoculation

03HandTendon and joint proximity

Test function carefully

04HostImmune and vascular reserve

Lower the referral threshold

Inspect dog-bite trauma

Look for crush injury, ragged laceration, devitalized tissue, fracture, vascular damage, and hidden injury beyond the skin edges.

Respect cat punctures

Cat teeth can inoculate tendon sheaths, joints, bone, and closed spaces. Small wounds on the hand can progress rapidly despite a mild initial appearance.

Protect function-critical sites

Bites to hands, face, feet, genitals, cartilage, joints, tendons, nerves, or vessels receive a lower threshold for direct evaluation.

Identify high-risk hosts

Asplenia, immune compromise, diabetes, decompensated liver disease, alcohol use disorder, vascular disease, edema, and limited follow-up increase the danger of serious infection.

0 of 1 answered
01Why is a small cat bite over a finger joint concerning?
Answer every question to submit.
123.03

Protect the Hand and Assess Both People

Human bites include direct bites and closed-fist injuries. Oral flora, joint penetration, tendon injury, tooth fragments, and blood exposure create risks for both people involved.

What to learn
  • Closed fist
  • Eikenella
  • Joint penetration
  • Blood exposure
  • Safeguarding
Human bite pathwayDirect bites and closed-fist injuries threaten tissue, joint, and blood exposure
01ExposeOpen the clenched hand

Inspect the true tract

02ExploreJoint, tendon, tooth fragment

Small wounds can be deep

03ScreenBlood in either direction

Assess both people

04EscalateHand surgery and infection care

Delay threatens function

Expose the true tract

A dorsal knuckle wound after striking teeth is examined with the hand positioned as during injury because opening the fist can move skin away from the deeper tract.

Assume deep anatomy is possible

Assess tendon excursion, joint pain, tooth fragments, fracture, infection, and delayed presentation. Suspected joint or tendon involvement requires urgent surgical evaluation.

Assess both exposure directions

Visible blood can expose the bitten person through the wound and the person biting through oral mucosa. Record whose blood contacted which tissue.

Preserve safety and dignity

Consider assault, intimate-partner violence, child or elder abuse, self-defense, occupational exposure, and barriers to follow-up without replacing clinical care with judgment.

0 of 1 answered
01How should a suspected closed-fist bite over a knuckle be examined?
Answer every question to submit.
123.04

Reduce Inoculum and Preserve Function

Immediate soap-and-water cleansing and copious irrigation are active treatment. Exploration, imaging, debridement, drainage, and closure decisions follow anatomy and contamination.

What to learn
  • Soap and water
  • Irrigation
  • Foreign body
  • Debridement
  • Closure
Wound-care sequenceControl bleeding, irrigate, explore, debride selectively, and plan closure
01CleanSoap and copious water

Reduce inoculum early

02InspectDepth and foreign material

Do not probe blindly

03PreserveViable tissue and function

Debride by indication

04CloseSite and contamination decide

Follow-up remains essential

Clean immediately

Wash with soap and water and irrigate thoroughly. Do not postpone cleansing while waiting for rabies, tetanus, or antibiotic decisions.

Explore safely

Look for retained teeth, devitalized tissue, joint penetration, tendon injury, fracture, and foreign material. Do not probe blindly or remove deeply embedded objects casually.

Debride and drain by indication

Remove devitalized tissue selectively and drain abscesses when required. Procedure, imaging, or specialist care can be more important than changing oral antibiotics.

Choose closure deliberately

Face, hand, puncture, crush, contamination, delay, infection, tissue loss, host risk, and follow-up determine primary closure, delayed closure, or open management.

0 of 1 answered
01What should occur promptly after a credible bite exposure?
Answer every question to submit.
123.05

Match Therapy to Oral Flora and Host Risk

Bite infections are frequently polymicrobial. Animal oral flora, human oral flora, skin organisms, anaerobes, wound depth, devitalized tissue, and host reserve determine the microbial problem.

What to learn
  • Pasteurella
  • Eikenella
  • Anaerobes
  • Capnocytophaga
  • Polymicrobial
Polymicrobial ecologyMouth flora, skin flora, wound conditions, and host reserve shape infection
01AnimalPasteurella and mixed flora

Rapid local infection can occur

02HumanEikenella and anaerobes

Common narrow drugs can fail

03HostCapnocytophaga risk

Asplenia raises urgency

04DepthAbscess, joint, bone

Source control matters

Recognize animal oral flora

Pasteurella can cause rapid local infection after dog or cat bites. Streptococci, staphylococci, Capnocytophaga, and anaerobes can also contribute.

Recognize human oral flora

Human bites can include streptococci, Staphylococcus aureus, Eikenella corrodens, and multiple anaerobic organisms.

Protect high-risk hosts

Capnocytophaga can rarely cause fulminant sepsis after dog or cat saliva exposure, especially with asplenia, immune compromise, or alcohol use disorder.

Think by compartment

Purulence, abscess, tendon sheath, joint, bone, necrosis, and systemic illness change culture, source-control, route, and duration decisions.

0 of 1 answered
01Why is clindamycin alone an unreliable choice for a human bite?
Answer every question to submit.
123.06

Use Preemptive Antibiotics Where Risk Justifies Them

Antibiotics are not a substitute for wound care and are not required for every superficial exposure. Benefit is more plausible in human bites and high-risk animal wounds, anatomy, hosts, or closure plans.

What to learn
  • High-risk wound
  • Human bite
  • Amoxicillin clavulanate
  • Allergy
  • Short course
Preemptive decisionUse wound, anatomy, delay, closure, and host risk instead of treating every bite alike
01High riskHand, face, foot, deep puncture

Benefit is more plausible

02Host riskImmune, spleen, liver, vascular

Complications can accelerate

03CoverageAerobes plus anaerobes

Match oral flora

04RecheckTwenty-four to forty-eight hours

Prophylaxis is not closure

Identify high-risk exposure

Hand, face, foot, genital, cartilage, puncture, crush, edema, delayed presentation, deep injury, primary closure, and significant tissue destruction increase concern.

Identify high-risk host

Immune compromise, asplenia, diabetes, decompensated liver disease, poor circulation, edema, and limited follow-up lower the threshold for preemptive therapy.

Preserve the needed spectrum

Amoxicillin clavulanate is a common oral first choice. Allergy alternatives must still cover relevant Pasteurella, Eikenella, streptococci, staphylococci, and anaerobes.

Close the stewardship loop

Use the recommended prophylaxis duration, explain adverse effects, and reassess rather than extending antibiotics automatically.

0 of 1 answered
01Which exposure most strongly supports antibiotic prophylaxis assessment?
Answer every question to submit.
123.07

Treat Infection and Secure Source Control

Established infection requires severity classification, useful microbiology, aerobic and anaerobic coverage, organ and allergy review, and prompt management of abscess or deep-space disease.

What to learn
  • Cellulitis
  • Abscess
  • Culture
  • Mixed coverage
  • Source control
Infection pathwayClassify severity, obtain useful cultures, cover mixed flora, and secure source control
01RecognizePain, swelling, pus, spread

Trajectory defines concern

02CultureDrainage or severe disease

Use results to narrow

03TreatAerobic and anaerobic cover

Account for allergy and organs

04EscalateAbscess, joint, bone, sepsis

Procedure can be decisive

Recognize progression

Increasing pain, warmth, swelling, pus, odor, spreading color change, lymphangitis, fever, systemic illness, or functional decline supports infection.

Culture selectively

Obtain drainage, abscess material, deep tissue, or another high-quality specimen for severe, unusual, recurrent, or treatment-failing infection when results can change care.

Cover mixed flora

Use therapy active against relevant aerobes and anaerobes. Verify allergy, renal and hepatic function, pregnancy, age, weight, interactions, severity, and oral versus intravenous feasibility.

Escalate deep disease

Abscess, tenosynovitis, septic arthritis, osteomyelitis, necrotizing infection, severe cellulitis, and sepsis require urgent imaging, procedure, specialist care, or parenteral therapy.

0 of 1 answered
01Which finding most strongly suggests a deep-space bite infection?
Answer every question to submit.
123.08

Use Public Health to Determine Rabies Risk

Rabies risk depends on a credible exposure route, mammal species, geography, animal behavior and health, severity, travel, and whether the animal can be observed or tested.

What to learn
  • Bat
  • Reservoir species
  • Geography
  • Ten-day observation
  • Public health
Rabies assessmentSpecies, geography, behavior, exposure route, and animal availability determine the public-health pathway
01ExposureBite, scratch, saliva to tissue

Objects do not transmit rabies

02AnimalBat and reservoir species

Risk varies by place

03ObserveHealthy dog, cat, ferret

Coordinate ten-day observation

04DecidePublic-health consultation

Do not guess alone

Define a credible exposure

Bites, scratches, and infectious saliva contacting broken skin or mucosa can transmit rabies. Clothing, bedding, and intact objects do not.

Use species and geography

Bats are a risk across most of the United States. Raccoon, skunk, fox, mongoose, and dog risk varies by location and travel history.

Use animal availability correctly

A healthy dog, cat, or ferret can undergo a formal ten-day observation under public-health coordination. Illness during observation triggers immediate reporting and testing decisions.

Escalate bat and severe exposure

Direct bat contact that cannot be definitively excluded, reservoir species, multiple wounds, head or neck exposure, young children, and foreign-country dog exposure need prompt assessment.

0 of 1 answered
01Who should guide the final decision about rabies PEP after an uncertain animal exposure?
Answer every question to submit.
123.09

Build Immediate and Active Rabies Protection

When PEP is indicated, immediate wound cleansing reduces inoculum, HRIG supplies passive antibody for unvaccinated people, and vaccine generates active immunity on a defined schedule.

What to learn
  • Wound cleansing
  • HRIG
  • Day zero
  • Four-dose series
  • Immune compromise
Postexposure protectionWound cleansing, immune globulin, and vaccine create immediate and active protection
01CleanSoap, water, virucidal agent

Begin immediately

02HRIGInfiltrate around wounds

One dose for unvaccinated people

03VaccineDays zero, three, seven, fourteen

Use the deltoid or thigh

04AdaptPrior vaccine or immune compromise

Regimen changes

Start with wound cleansing

Wash all wounds thoroughly with soap and water. A virucidal agent such as povidone iodine can be used for irrigation when available.

Place HRIG correctly

For an unvaccinated person, give HRIG once and infiltrate as much as anatomically feasible around all wounds. Give any remainder intramuscularly distant from vaccine. Do not exceed the recommended dose.

Give vaccine correctly

Unvaccinated immunocompetent people receive vaccine on days zero, three, seven, and fourteen. Use the deltoid or age-appropriate thigh, never the gluteal area.

Adapt for immune history

Previously vaccinated people receive vaccine on days zero and three without HRIG. Immunocompromised unvaccinated people receive an additional day twenty-eight dose and require response planning.

0 of 1 answered
01What is the standard vaccine schedule for an unvaccinated immunocompetent person receiving rabies PEP?
Answer every question to submit.
123.10

Close Tetanus, Blood Exposure, and Follow-up Gaps

Bite care is incomplete until tetanus protection, human-bite blood exposure, infection trajectory, animal status, function, adverse effects, reporting, and safeguarding have explicit owners and dates.

What to learn
  • Tetanus
  • HIV nPEP
  • Hepatitis B
  • Return rule
  • Safeguarding
Closed-loop preventionTetanus, bloodborne assessment, safeguarding, infection review, and function complete care
01TetanusDirty or major wound rules

Document the series

02BloodVisible blood changes risk

Human bites expose both people

03ProtectSafeguarding and reporting

Context matters

04ReturnFunction, infection, systemic signs

Set a dated checkpoint

Apply tetanus wound rules

Saliva-contaminated bites are dirty or major wounds. Use documented primary series, time since last dose, HIV, and severe immunodeficiency to determine vaccine and TIG.

Evaluate visible-blood exposure

Human bites without blood exposure do not routinely indicate HIV nPEP. Visibly bloody saliva contacting susceptible tissue can require urgent case-by-case HIV, hepatitis B, and hepatitis C evaluation.

Reassess early

High-risk and infected bites need a clear twenty-four to forty-eight-hour checkpoint. Worsening at any time, systemic illness, disproportionate pain, lymphangitis, or functional decline requires escalation.

Track the whole event

Document antibiotics, adverse effects, wound progress, motion, sensation, animal observation or testing, rabies plan, reporting, safeguarding, and access barriers.

0 of 1 answered
01When is HIV nPEP routinely unnecessary after a human bite?
Answer every question to submit.

Check the connections.

Each attempt draws 10 questions from the complete 112 question bank.

112 questions in this module bank10 questions per attempt

Each attempt draws a fresh set and rearranges the answer choices.

Current clinical foundation.

Lecture material was synthesized with the following contemporary guidance. Verify local policy and current guidance before applying clinical information.

  1. CDC Rabies PEP Guidance
  2. CDC Rabies Clinical Screening
  3. CDC Rabies Veterinary Observation
  4. CDC Capnocytophaga Clinical Overview
  5. CDC 2025 Nonoccupational HIV PEP
  6. CDC Tetanus Wound Management
  7. IDSA Skin and Soft Tissue Infection Guideline
  8. NICE Human and Animal Bites
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